Short and Long-Term Effects of hVEGF-A(165) in Cre-Activated Transgenic Mice

We have generated a transgenic mouse where hVEGF-A(165) expression has been silenced with loxP-STOP fragment, and we used this model to study the effects of hVEGF-A(165) over-expression in mice after systemic adenovirus mediated Cre-gene transfer. Unlike previous conventional transgenic models, this...

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Detalhes bibliográficos
Main Authors: Leppänen, Pia, Kholová, Ivana, Mähönen, Anssi J., Airenne, Kari, Koota, Suvi, Mansukoski, Hannu, Närväinen, Johanna, Wirzenius, Maria, Alhonen, Leena, Jänne, Juhani, Alitalo, Kari, Ylä-Herttuala, Seppo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762316/
https://ncbi.nlm.nih.gov/pubmed/17183639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000013
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