IL-6 blocks a discrete early step in lymphopoiesis

Animals lacking Src homology 2 domain-containing inositol 5-phosphatase (SHIP) display a reduction in lymphopoiesis and a corresponding enhancement of myelopoiesis. These effects are mediated at least in part by elevated levels of interleukin 6 (IL-6). Here, we show the lymphopoiesis block in SHIP(–...

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Detalhes bibliográficos
Main Authors: Maeda, Kazuhiko, Baba, Yoshihiro, Nagai, Yoshinori, Miyazaki, Kozo, Malykhin, Alexander, Nakamura, Koji, Kincade, Paul W., Sakaguchi, Nobuo, Coggeshall, K. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Hematopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1761686/
https://ncbi.nlm.nih.gov/pubmed/15831701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0456
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