Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus–prone B6.Sle1.Yaa animals

We previously reported the inhibitory action of interleukin-6 (IL-6) on B lymphopoiesis with SHIP(−/−) mice and showed that IL-6 biases lineage commitment toward myeloid cell fates in vitro and in vivo. Because elevated IL-6 is a feature of chronic inflammatory diseases, we applied an animal model o...

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Detalhes bibliográficos
Main Authors: Maeda, Kenichiro, Malykhin, Alex, Teague-Weber, Brittany N., Sun, Xiao-Hong, Farris, A. Darise, Coggeshall, K. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680362/
https://ncbi.nlm.nih.gov/pubmed/19224760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-192559
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