Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible

The murine c-fms (Csf1r) gene encodes the macrophage colony-stimulating factor receptor, which is essential for macrophage development. It is expressed at a low level in haematopoietic stem cells and is switched off in all non-macrophage cell types. To examine the role of chromatin structure in this...

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Pubblicato in:	EMBO J
Autori principali:	Tagoh, Hiromi, Schebesta, Alexandra, Lefevre, Pascal, Wilson, Nicola, Hume, David, Busslinger, Meinrad, Bonifer, Constanze
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2004
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15483629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600421
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