Development of a novel site-specific mutagenesis assay using MALDI-ToF MS (SSMA-MS)

We have developed and validated a novel site-specific mutagenesis assay, termed SSMA-MS, which incorporates MALDI-ToF mass spectrometry (MALDI-MS) analysis as a means of determining the mutations induced by a single DNA adduct. The assay involves ligating an adducted deoxyoligonucleotide into supF c...

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Главные авторы: McLuckie, Keith I. E., Lamb, John H., Sandhu, Jatinderpal K., Pearson, Helen L., Brown, Karen, Farmer, Peter B., Jones, Donald J. L.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2006
Предметы:
Methods Online
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1761429/
https://ncbi.nlm.nih.gov/pubmed/17130165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl745
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