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Development of a novel site-specific mutagenesis assay using MALDI-ToF MS (SSMA-MS)
We have developed and validated a novel site-specific mutagenesis assay, termed SSMA-MS, which incorporates MALDI-ToF mass spectrometry (MALDI-MS) analysis as a means of determining the mutations induced by a single DNA adduct. The assay involves ligating an adducted deoxyoligonucleotide into supF c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1761429/ https://ncbi.nlm.nih.gov/pubmed/17130165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl745 |
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