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Protein folding and unfolding in microseconds to nanoseconds by experiment and simulation
The Engrailed Homeodomain protein has the highest refolding and unfolding rate constants directly observed to date. Temperature jump relaxation measurements gave a refolding rate constant of 37,500 s(−1) in water at 25°C, rising to 51,000 s(−1) around 42°C. The unfolding rate constant was 1,100 s(−1...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC17607/ https://ncbi.nlm.nih.gov/pubmed/11087839 |
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