Protection by imidazol(ine) drugs and agmatine of glutamate-induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor

1. This study was designed to assess the potential neuroprotective effect of several imidazol(ine) drugs and agmatine on glutamate-induced necrosis and on apoptosis induced by low extracellular K(+) in cultured cerebellar granule cells. 2. Exposure (30 min) of energy deprived cells to L-glutamate (1...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Olmos, Gabriel, DeGregorio-Rocasolano, Nuria, Regalado, M Paz, Gasull, Teresa, Boronat, M Assumpció, Trullas, Ramón, Villarroel, Alvaro, Lerma, Juan, García-Sevilla, Jesús A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1999
Pynciau:
Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760666/
https://ncbi.nlm.nih.gov/pubmed/10455281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702679
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