Protection by imidazol(ine) drugs and agmatine of glutamate-induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor

1. This study was designed to assess the potential neuroprotective effect of several imidazol(ine) drugs and agmatine on glutamate-induced necrosis and on apoptosis induced by low extracellular K(+) in cultured cerebellar granule cells. 2. Exposure (30 min) of energy deprived cells to L-glutamate (1...

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Autors principals: Olmos, Gabriel, DeGregorio-Rocasolano, Nuria, Regalado, M Paz, Gasull, Teresa, Boronat, M Assumpció, Trullas, Ramón, Villarroel, Alvaro, Lerma, Juan, García-Sevilla, Jesús A
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1760666/
https://ncbi.nlm.nih.gov/pubmed/10455281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702679
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