In vitro evaluation of the determinants of bactericidal activity of ampicillin dosing regimens against Escherichia coli.

An in vitro flow model was used to examine the influence of peak concentration (Cmax), the area under the antibiotic concentration-time curve (AUC), the magnitude of AUC above the MIC, and the aggregate time the antibiotic concentration exceeds the MIC (TMIC) on the bactericidal effect of ampicillin...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	White, C A, Toothaker, R D, Smith, A L, Slattery, J T
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1989
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2675754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.7.1046
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