Efficacy of ampicillin-sulbactam is not dependent upon maintenance of a critical ratio between components: sulbactam pharmacokinetics in pharmacodynamic interactions.

An in vitro pharmacokinetic model (IVPM) and a mouse model of lethal bacteremia were used to compare the pharmacodynamics of ampicillin-sulbactam when the two components were dosed simultaneously and in sequence against TEM-1-producing Escherichia coli. The challenge isolates included three strains...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Alexov, M, Lister, P D, Sanders, C C
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC163559/
https://ncbi.nlm.nih.gov/pubmed/8913448
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki