In vitro evaluation of the determinants of bactericidal activity of ampicillin dosing regimens against Escherichia coli.
An in vitro flow model was used to examine the influence of peak concentration (Cmax), the area under the antibiotic concentration-time curve (AUC), the magnitude of AUC above the MIC, and the aggregate time the antibiotic concentration exceeds the MIC (TMIC) on the bactericidal effect of ampicillin...
保存先:
| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1989
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2675754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.7.1046 |
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