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3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase.

Reverse transcriptase was purified from human immunodeficiency virus (HIV). It utilized the artificial primer-template poly(rA)-oligo(dT)12-18 more efficiently than activated calf thymus DNA, poly(rI)-oligo(dC)12-18, poly(rC)-oligo(dG)12-18, or poly(rCm)-oligo(dG)12-18. Maximum activity was observed...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: St Clair, M H, Richards, C A, Spector, T, Weinhold, K J, Miller, W H, Langlois, A J, Furman, P A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2449866/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.12.1972
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