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Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel–Lindau protein

Inactivation of the von Hippel–Lindau (VHL) tumor suppressor gene is linked to the hereditary VHL disease and sporadic clear cell renal cell carcinomas (CCRCC). VHL-associated tumors are highly vascularized, a characteristic associated with overproduction of vascular endothelial growth factor (VEGF)...

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Bibliographic Details
Published in:EMBO J
Main Authors: Na, Xi, Duan, Hai Ou, Messing, Edward M., Schoen, Susan R., Ryan, Charlotte K., di Sant’Agnese, P.Anthony, Golemis, Erica A., Wu, Guan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2003
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12912922/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg410
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