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Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel–Lindau protein

Inactivation of the von Hippel–Lindau (VHL) tumor suppressor gene is linked to the hereditary VHL disease and sporadic clear cell renal cell carcinomas (CCRCC). VHL-associated tumors are highly vascularized, a characteristic associated with overproduction of vascular endothelial growth factor (VEGF)...

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Detalhes bibliográficos
Main Authors: Na, Xi, Duan, Hai Ou, Messing, Edward M., Schoen, Susan R., Ryan, Charlotte K., di Sant’Agnese, P.Anthony, Golemis, Erica A., Wu, Guan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC175799/
https://ncbi.nlm.nih.gov/pubmed/12912922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg410
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