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Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel–Lindau protein

Inactivation of the von Hippel–Lindau (VHL) tumor suppressor gene is linked to the hereditary VHL disease and sporadic clear cell renal cell carcinomas (CCRCC). VHL-associated tumors are highly vascularized, a characteristic associated with overproduction of vascular endothelial growth factor (VEGF)...

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Publicat a:EMBO J
Autors principals: Na, Xi, Duan, Hai Ou, Messing, Edward M., Schoen, Susan R., Ryan, Charlotte K., di Sant’Agnese, P.Anthony, Golemis, Erica A., Wu, Guan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12912922/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg410
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