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Differential regulation of NFAT and SRF by the B cell receptor via a PLCγ–Ca(2+)-dependent pathway

NFAT and SRF are important in the regulation of proliferation and cytokine production in lymphocytes. NFAT activation by the B cell receptor (BCR) occurs via the PLCγ–Ca(2+)–calcineurin pathway, however how the BCR activates SRF is unclear. We show here that like NFAT, BCR regulation of SRF occurs v...

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Bibliografische gegevens
Hoofdauteurs: Hao, Shengli, Kurosaki, Tomohiro, August, Avery
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC175791/
https://ncbi.nlm.nih.gov/pubmed/12912915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg401
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