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Amplification of receptor signalling by Ca(2+) entry-mediated translocation and activation of PLCγ2 in B lymphocytes

In non-excitable cells, receptor-activated Ca(2+) signalling comprises initial transient responses followed by a Ca(2+) entry-dependent sustained and/or oscillatory phase. Here, we describe the molecular mechanism underlying the second phase linked to signal amplification. An in vivo inositol 1,4,5-...

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Detalhes bibliográficos
Main Authors: Nishida, Motohiro, Sugimoto, Kenji, Hara, Yuji, Mori, Emiko, Morii, Takashi, Kurosaki, Tomohiro, Mori, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC212724/
https://ncbi.nlm.nih.gov/pubmed/12970180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg457
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