Detoxification of the Helicobacter pylori cytotoxin.

Treatment of the Helicobacter pylori vacuolating cytotoxin with very low concentrations of formaldehyde resulted in abrogation of toxic activity in both a HeLa cell vacuolation assay and an in vivo assay of gastric epithelial damage. Detoxification had only a minimal effect on the integrity of the o...

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Main Authors: Manetti, R, Massari, P, Marchetti, M, Magagnoli, C, Nuti, S, Lupetti, P, Ghiara, P, Rappuoli, R, Telford, J L
Formato: Artigo
Idioma:Inglês
Publicado: 1997
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC175662/
https://ncbi.nlm.nih.gov/pubmed/9353041
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