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Methotrexate ameliorates T cell dependent autoimmune arthritis and encephalomyelitis but not antibody induced or fibroblast induced arthritis

Objective: To investigate the mode of action of methotrexate (MTX) in different types of models for rheumatoid arthritis (RA) and multiple sclerosis (MS). Methods: Models for RA and MS were selected known to have different pathogenesis—that is, fibroblast induced arthritis in SCID mice, collagen ind...

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Detalhes bibliográficos
Main Authors: Lange, F, Bajtner, E, Rintisch, C, Nandakumar, K, Sack, U, Holmdahl, R
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755430/
https://ncbi.nlm.nih.gov/pubmed/15345503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.026120
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