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Divergent evolution of membrane protein topology: The Escherichia coli RnfA and RnfE homologues

Although the molecular evolution of protein tertiary structure and enzymatic activity has been studied for decades, little attention has been paid to the evolution of membrane protein topology. Here, we show that two closely related polytopic inner membrane proteins from Escherichia coli have evolve...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sääf, Annika, Johansson, Marie, Wallin, Erik, von Heijne, Gunnar
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17552/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8540
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