Divergent evolution of membrane protein topology: The Escherichia coli RnfA and RnfE homologues

Although the molecular evolution of protein tertiary structure and enzymatic activity has been studied for decades, little attention has been paid to the evolution of membrane protein topology. Here, we show that two closely related polytopic inner membrane proteins from Escherichia coli have evolve...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Sääf, Annika, Johansson, Marie, Wallin, Erik, von Heijne, Gunnar
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17552/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8540
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