Laddar...

Genetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammals

By using both genetic and biochemical approaches, we have investigated the physiological role of Shp-2, a cytoplasmic tyrosine phosphatase with two Src homology 2 domains, in signaling pathways downstream of epidermal growth factor receptor (EGF-R). In previous studies, a targeted deletion mutation...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Qu, Cheng-Kui, Yu, Wen-Mei, Azzarelli, Biagio, Feng, Gen-Sheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC17550/
https://ncbi.nlm.nih.gov/pubmed/10411909
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!