Importance of NF-κB in rheumatoid synovial tissues: in situ NF-κB expression and in vitro study using cultured synovial cells

OBJECTIVES—To examine whether inhibition of NF-κB induces apoptosis of human synovial cells stimulated by tumour necrosis factor α (TNFα), interleukin 1β (IL1β), and anti-Fas monoclonal antibody (mAb).
METHODS—The expression of proliferating cell nuclear antigen (PCNA), NF-κB, and the presence of ap...

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Detalhes bibliográficos
Main Authors: Yamasaki, S, Kawakami, A, Nakashima, T, Nakamura, H, Kamachi, M, Honda, S, Hirai, Y, Hida, A, Ida, H, Migita, K, Kawabe, Y, Koji, T, Furuichi, I, Aoyagi, T, Eguchi, K
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753739/
https://ncbi.nlm.nih.gov/pubmed/11406522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.60.7.678
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