Anti-apoptogenic function of TGFß1 for human synovial cells: TGFß1 protects cultured synovial cells from mitochondrial perturbation induced by several apoptogenic stimuli

Methods: Isolated synovial cells, treated or not with TGFß1, were cultured in the presence or absence of anti-Fas IgM, proteasome inhibitor Z-Leu-Leu-Leu-aldehyde (LLL-CHO), etoposide, or C2-ceramide. After cultivation, apoptosis of synovial cells was examined by the presence of hypodiploid DNA(+) c...

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Bibliographische Detailangaben
Hauptverfasser: Kawakami, A, Urayama, S, Yamasaki, S, Hida, A, Miyashita, T, Kamachi, M, Nakashima, K, Tanaka, F, Ida, H, Kawabe, Y, Aoyagi, T, Furuichi, I, Migita, K, Origuchi, T, Eguchi, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Concise Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754706/
https://ncbi.nlm.nih.gov/pubmed/14672900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.014159
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