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Esculetin inhibits cartilage resorption induced by interleukin 1α in combination with oncostatin M
OBJECTIVE—To determine if a new inhibitor, esculetin (EST), can block resorption of cartilage. METHODS—Interleukin 1α (IL1α, 0.04-5 ng/ml) and oncostatin M (OSM, 0.4-50 ng/ml) were used to stimulate the release of proteoglycan and collagen from bovine nasal cartilage and human articular cartilage in...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2001
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1753478/ https://ncbi.nlm.nih.gov/pubmed/11156550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.60.2.158 |
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