Esculetin inhibits cartilage resorption induced by interleukin 1α in combination with oncostatin M

OBJECTIVE—To determine if a new inhibitor, esculetin (EST), can block resorption of cartilage.
METHODS—Interleukin 1α (IL1α, 0.04-5 ng/ml) and oncostatin M (OSM, 0.4-50 ng/ml) were used to stimulate the release of proteoglycan and collagen from bovine nasal cartilage and human articular cartilage in...

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Detalhes bibliográficos
Main Authors: Elliott, S, Rowan, A, Carrere, S, Koshy, P, Catterall, J, Cawston, T
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753478/
https://ncbi.nlm.nih.gov/pubmed/11156550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.60.2.158
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