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Blockade of endogenous interleukin 12 results in suppression of murine streptococcal cell wall arthritis by enhancement of interleukin 10 and interleukin 1Ra

OBJECTIVE—The goal of this study was to investigate the role of endogenous interleukin 12 (IL12) in acute murine streptococcal cell wall (SCW) arthritis.
METHODS—C57black/6 mice were injected intraperitoneally with rat anti-murine IL12 (C17.8), shortly before induction of arthritis by intra-articula...

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Detalhes bibliográficos
Main Authors: Joosten, L., Helsen, M., van den Berg, W. B
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753084/
https://ncbi.nlm.nih.gov/pubmed/10700428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.59.3.196
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