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Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis

INTRODUCTION: Rheumatoid arthritis (RA) is associated with an increased production of a range of cytokines including tumour necrosis factor (TNF)-α and interleukin (IL)-1, which display potent proinflammatory actions that are thought to contribute to the pathogenesis of the disease. Although TNF-α s...

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Detalhes bibliográficos
Publicado no:Arthritis Res
Principais autores: Joosten, Leo AB, Lubberts, Erik, Helsen, Monique MA, Saxne, Tore, Coenen-de Roo, Christina JJ, Heinegård, Dick, van den Berg, Wim B
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17779/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11056663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar14
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