GM‐CSF neutralisation suppresses inflammation and protects cartilage in acute streptococcal cell wall arthritis of mice

OBJECTIVE: The pathogenic involvement of granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) in arthritis has been put forward. We have investigated the therapeutic effect of GM‐CSF neutralisation in the streptococcal cell wall (SCW) arthritis model in mice. In this model, the pathogenic contr...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Plater‐Zyberk, C, Joosten, L A B, Helsen, M M A, Hepp, J, Baeuerle, P A, van den Berg, W B
Format: Artigo
Langue:Inglês
Publié: BMJ Group 2007
Sujets:
Extended Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856054/
https://ncbi.nlm.nih.gov/pubmed/17020908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.057182
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