GM‐CSF neutralisation suppresses inflammation and protects cartilage in acute streptococcal cell wall arthritis of mice

OBJECTIVE: The pathogenic involvement of granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) in arthritis has been put forward. We have investigated the therapeutic effect of GM‐CSF neutralisation in the streptococcal cell wall (SCW) arthritis model in mice. In this model, the pathogenic contr...

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Detalhes bibliográficos
Main Authors: Plater‐Zyberk, C, Joosten, L A B, Helsen, M M A, Hepp, J, Baeuerle, P A, van den Berg, W B
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856054/
https://ncbi.nlm.nih.gov/pubmed/17020908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2006.057182
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