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Intranasal immunization with C5a peptidase prevents nasopharyngeal colonization of mice by the group A Streptococcus.

Early inflammatory events are initiated by phased production of C5a and interleukin-8 in tissue. Most serotypes of group A streptococci express a surface-bound peptidase (SCPA) which specifically cleaves mouse and human C5a chemotaxins. This study investigates the impact of SCPA on colonization of t...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Ji, Y, Carlson, B, Kondagunta, A, Cleary, P P
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175287/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9169735/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.6.2080-2087.1997
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