Intranasal immunization with C5a peptidase prevents nasopharyngeal colonization of mice by the group A Streptococcus.

Early inflammatory events are initiated by phased production of C5a and interleukin-8 in tissue. Most serotypes of group A streptococci express a surface-bound peptidase (SCPA) which specifically cleaves mouse and human C5a chemotaxins. This study investigates the impact of SCPA on colonization of t...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Ji, Y, Carlson, B, Kondagunta, A, Cleary, P P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175287/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9169735/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.6.2080-2087.1997
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