Immunization with C5a Peptidase or Peptidase-Type III Polysaccharide Conjugate Vaccines Enhances Clearance of Group B Streptococci from Lungs of Infected Mice

Group B streptococci (GBS) are among the most common causes of life-threatening neonatal infections. Vaccine development since the late 1970s has focused on the capsular polysaccharides, but a safe, effective product is still not available. Our quest for a vaccine turned to the streptococcal C5a pep...

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Detalhes bibliográficos
Main Authors: Cheng, Qi, Debol, Steven, Lam, Hong, Eby, Ron, Edwards, Lorri, Matsuka, Yury, Olmsted, Stephen B., Cleary, P. Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130386/
https://ncbi.nlm.nih.gov/pubmed/12379721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6409-6415.2002
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