Hyaluronan production in human rheumatoid fibroblastic synovial lining cells is increased by interleukin 1β but inhibited by transforming growth factor β1

OBJECTIVES—To investigate the regulatory roles of interleukin 1β (IL1β), tumour necrosis factor α (TNFα), interferon γ (IFNγ) or transforming growth factor β1 (TGFβ1) on hyaluronan (HA) synthesis by human fibroblastic synovial lining cells.
METHODS—Concentrations of HA in culture supernatants of fib...

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Autors principals: Kawakami, M., Suzuki, K., Matsuki, Y., Ishizuka, T., Hidaka, T., Konishi, T., Matsumoto, M., Kataharada, K., Nakamura, H.
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Extended Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752477/
https://ncbi.nlm.nih.gov/pubmed/9893571
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