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Crystal Structure of the Agrin-responsive Immunoglobulin-like Domains 1 and 2 of the Receptor Tyrosine Kinase MuSK

Muscle-specific kinase (MuSK) is a receptor tyrosine kinase expressed exclusively in skeletal muscle, where it is required for formation of the neuromuscular junction (NMJ). MuSK is activated by agrin, a neuron-derived heparan sulfate proteoglycan. Here, we report the crystal structure of the agrin-...

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Detalhes bibliográficos
Main Authors: Stiegler, Amy L., Burden, Steven J., Hubbard, Stevan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752213/
https://ncbi.nlm.nih.gov/pubmed/17011580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.019
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