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Modulation of P-glycoprotein activity by cannabinoid molecules in HK-2 renal cells
1. Endogenous and synthetic cannabinoid molecules have been investigated as possible MDR-1/P-glycoprotein (P-gp) modulators in HK-2-immortalized renal cells, using calcein acetoxymethylester (calcein-AM) as a P-gp substrate. 2. Among the endocannabinoid molecules tested, anandamide (AEA), but not 2-...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Nature Publishing Group
2006
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751877/ https://ncbi.nlm.nih.gov/pubmed/16715117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706778 |
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