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Detection of multiple H(3) receptor affinity states utilizing [(3)H]A-349821, a novel, selective, non-imidazole histamine H(3) receptor inverse agonist radioligand

1. A-349821 is a selective histamine H(3) receptor antagonist/inverse agonist. Herein, binding of the novel non-imidazole H(3) receptor radioligand [(3)H]A-349821 to membranes expressing native or recombinant H(3) receptors from rat or human sources was characterized and compared with the binding of...

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Detalhes bibliográficos
Main Authors: Witte, David G, Yao, Betty Bei, Miller, Thomas R, Carr, Tracy L, Cassar, Steven, Sharma, Rahul, Faghih, Ramin, Surber, Bruce W, Esbenshade, Timothy A, Hancock, Arthur A, Krueger, Kathleen M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751875/
https://ncbi.nlm.nih.gov/pubmed/16715122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706752
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