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Peptides modified by myristoylation activate eNOS in endothelial cells through Akt phosphorylation

1. Myristoylated pseudosubstrate of PKCζ (mPS) – a synthetic myristoylated peptide with a sequence (13 amino acids) mimicking the endogenous PKCζ pseudosubstrate region – is considered a selective cell-permeable inhibitor of PKCζ. We present strong evidence that in endothelial cells the action of mP...

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Detalhes bibliográficos
Main Authors: Krotova, Karina, Hu, Hanbo, Xia, Shen-Ling, Belayev, Leonid, Patel, Jawaharlal M, Block, Edward R, Zharikov, Sergey
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751869/
https://ncbi.nlm.nih.gov/pubmed/16715118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706777
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