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Novel Peptide for Attenuation of Hypoxia-Induced Pulmonary Hypertension via Modulation of Nitric Oxide Release and Phosphodiesterase -5 Activity
Pulmonary vascular endothelial nitric oxide (NO) synthase (eNOS)-derived NO is the major stimulant of cyclic guanosine 5’ monophosphate (cGMP) production and NO/cGMP-dependent vasorelaxation in the pulmonary circulation. We recently synthesized multiple peptides and reported that an eleven amino aci...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335268/ https://ncbi.nlm.nih.gov/pubmed/22465621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2012.03.009 |
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