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Insensitivity of cardiac delayed-rectifier I(Kr) to tyrosine phosphorylation inhibitors and stimulators

1. The rapidly activating delayed-rectifying K(+) current (I(Kr)) in heart cells is an important determinant of repolarisation, and decreases in its density are implicated in acquired and inherited long QT syndromes. The objective of the present study on I(Kr) in guinea-pig ventricular myocytes was...

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Détails bibliographiques
Auteurs principaux: Missan, Sergey, Zhabyeyev, Pavel, Linsdell, Paul, McDonald, Terence F
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751861/
https://ncbi.nlm.nih.gov/pubmed/16715119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706776
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