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Insensitivity of cardiac delayed-rectifier I(Kr) to tyrosine phosphorylation inhibitors and stimulators

1. The rapidly activating delayed-rectifying K(+) current (I(Kr)) in heart cells is an important determinant of repolarisation, and decreases in its density are implicated in acquired and inherited long QT syndromes. The objective of the present study on I(Kr) in guinea-pig ventricular myocytes was...

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Detalhes bibliográficos
Main Authors: Missan, Sergey, Zhabyeyev, Pavel, Linsdell, Paul, McDonald, Terence F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751861/
https://ncbi.nlm.nih.gov/pubmed/16715119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706776
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