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Insensitivity of cardiac delayed-rectifier I(Kr) to tyrosine phosphorylation inhibitors and stimulators

1. The rapidly activating delayed-rectifying K(+) current (I(Kr)) in heart cells is an important determinant of repolarisation, and decreases in its density are implicated in acquired and inherited long QT syndromes. The objective of the present study on I(Kr) in guinea-pig ventricular myocytes was...

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Bibliographic Details
Main Authors: Missan, Sergey, Zhabyeyev, Pavel, Linsdell, Paul, McDonald, Terence F
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751861/
https://ncbi.nlm.nih.gov/pubmed/16715119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706776
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