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Selective phenylalkylamine block of I(Kr) over other K(+) currents in guinea-pig ventricular myocytes
1. Previous studies on verapamil and D600 have established that the Ca(2+)-channel blockers also inhibit delayed-rectifier K(+) currents in cardiac tissues and myocytes. However, estimated IC(50) values range over two to three orders of concentration, and it is unclear whether this reflects a high s...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572516/ https://ncbi.nlm.nih.gov/pubmed/11139462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703758 |
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