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Differential Rho-kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction

1. In airway smooth muscle (ASM), full and partial muscarinic receptor agonists have been described to have large differences in their ability to induce signal transduction, including Ca(2+)-mobilization. Despite these differences, partial agonists are capable of inducing a submaximal to maximal ASM...

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Autori principali: Schaafsma, Dedmer, Boterman, Mark, de Jong, Anne-Margreet, Hovens, Iris, Penninks, Jelte-Maarten, Nelemans, S Adriaan, Meurs, Herman, Zaagsma, Johan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751513/
https://ncbi.nlm.nih.gov/pubmed/16432505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706665
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