Differential Rho-kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction

1. In airway smooth muscle (ASM), full and partial muscarinic receptor agonists have been described to have large differences in their ability to induce signal transduction, including Ca(2+)-mobilization. Despite these differences, partial agonists are capable of inducing a submaximal to maximal ASM...

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Bibliografiske detaljer
Main Authors: Schaafsma, Dedmer, Boterman, Mark, de Jong, Anne-Margreet, Hovens, Iris, Penninks, Jelte-Maarten, Nelemans, S Adriaan, Meurs, Herman, Zaagsma, Johan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751513/
https://ncbi.nlm.nih.gov/pubmed/16432505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706665
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