Differential Rho-kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction

1. In airway smooth muscle (ASM), full and partial muscarinic receptor agonists have been described to have large differences in their ability to induce signal transduction, including Ca(2+)-mobilization. Despite these differences, partial agonists are capable of inducing a submaximal to maximal ASM...

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Hlavní autoři: Schaafsma, Dedmer, Boterman, Mark, de Jong, Anne-Margreet, Hovens, Iris, Penninks, Jelte-Maarten, Nelemans, S Adriaan, Meurs, Herman, Zaagsma, Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751513/
https://ncbi.nlm.nih.gov/pubmed/16432505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706665
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