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Prostaglandin E(2) activates EP(2) receptors to inhibit human lung mast cell degranulation
1. The prostanoid, PGE(2), is known to inhibit human lung mast cell activity. The aim of the present study was to characterize the EP receptor that mediates this effect. 2. PGE(2) (pEC(50), 5.8±0.1) inhibited the IgE-mediated release of histamine from mast cells in a concentration-dependent manner....
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751511/ https://ncbi.nlm.nih.gov/pubmed/16432506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706664 |
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