Prostaglandin E(2) Prevents Hyperosmolar-Induced Human Mast Cell Activation through Prostanoid Receptors EP(2) and EP(4)

BACKGROUND: Mast cells play a critical role in allergic and inflammatory diseases, including exercise-induced bronchoconstriction (EIB) in asthma. The mechanism underlying EIB is probably related to increased airway fluid osmolarity that activates mast cells to the release inflammatory mediators. Th...

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Main Authors: Torres-Atencio, Ivonne, Ainsua-Enrich, Erola, de Mora, Fernando, Picado, César, Martín, Margarita
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203853/
https://ncbi.nlm.nih.gov/pubmed/25329458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110870
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