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Spectrin Domains Lose Cooperativity in Forced Unfolding
Spectrin is a multidomain cytoskeletal protein, the component three-helix bundle domains are expected to experience mechanical force in vivo. In thermodynamic and kinetic studies, neighboring domains of chicken brain α-spectrin R16 and R17 have been shown to behave cooperatively. Is this cooperativi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751415/ https://ncbi.nlm.nih.gov/pubmed/17085494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.093690 |
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