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Detection and Characterization of Partially Unfolded Oligomers of the SH3 Domain of α-Spectrin

For the purpose of equilibrium and kinetic folding-unfolding studies, the SH3 domain of α-spectrin (spc-SH3) has long been considered a classic two-state folding protein. In this work we have indeed observed that the thermal unfolding curves of spc-SH3 measured at pH 3.0 by differential scanning cal...

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Detalhes bibliográficos
Main Authors: Casares, Salvador, Sadqi, Mourad, López-Mayorga, Obdulio, Conejero-Lara, Francisco, van Nuland, Nico A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304089/
https://ncbi.nlm.nih.gov/pubmed/15041678
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