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Structural Features of Parathyroid Hormone Receptor Coupled to Gα(S)-Protein

The molecular basis of the activation of G-proteins by the G-protein coupled receptor for parathyroid hormone (PTH) is unknown. Employing a combination of NMR methods and computer-based structural refinement, structural features involved in the activation of Gα(s) by the PTH receptor (PTH1R) have be...

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Main Authors: Plati, Jessica, Tsomaia, Natia, Piserchio, Andrea, Mierke, Dale F.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751412/
https://ncbi.nlm.nih.gov/pubmed/17040990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.094813
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