Neuroprotection associated with alternative splicing of NMDA receptors in rat cortical neurons

1. Exposure of cultured cortical neurons to elevated extracellular K(+) concentrations (25 mM) induces membrane depolarization and an increase in action-potential firing. 2. Long-term high K(+) treatment was associated with an increased neuronal cell death. 3. In surviving neurons, multiple changes...

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Main Authors: Jaekel, Beate, Mühlberg, Katja, Garcia de Arriba, Susana, Reichenbach, Andreas, Verdaguer, Ester, Pallas, Mercè, Camins, Antoni, Nörenberg, Wolfgang, Allgaier, Clemens
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751340/
https://ncbi.nlm.nih.gov/pubmed/16314856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706471
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