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Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin
1. In the spontaneously hypertensive rat (SHR) and aging Wistar–Kyoto rats (WKY), acetylcholine releases an endothelium-derived contracting factor (EDCF) produced by endothelial cyclooxygenase-1, which stimulates thromboxane A(2) receptors (TP receptors) on vascular smooth muscle. The purpose of the...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751221/ https://ncbi.nlm.nih.gov/pubmed/16158068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706390 |
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